article Open AccessTop 1% cited
Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice
Diabetes · 2008 · Vol. 57(6) · pp. 1470–1481
Patrice D. Cani✉(Hôpital Rangueil)Rodrigo Bibiloni(Nestlé (Switzerland))Claude Knauf(Hôpital Rangueil)Aurélie Waget(Hôpital Rangueil)Audrey M. Neyrinck(UCLouvain)Nathalie M. Delzenne(UCLouvain)Rémy Burcelin(Hôpital Rangueil)
Abstract
This new finding demonstrates that changes in gut microbiota controls metabolic endotoxemia, inflammation, and associated disorders by a mechanism that could increase intestinal permeability. It would thus be useful to develop strategies for changing gut microbiota to control, intestinal permeability, metabolic endotoxemia, and associated disorders.
Gut microbiota and healthDiet and metabolism studiesDietary Effects on HealthGut floraInflammationEndocrinologyIntestinal permeabilityInternal medicineBiologyLipopolysaccharideDiabetes mellitusAdipose tissueObesity
MeSH terms
AnimalsAnti-Bacterial AgentsBacteroidesBase SequenceBifidobacteriumCecumCrosses, GeneticDiabetes Mellitus, ExperimentalFecesFemaleGenotypeInflammationLactobacillusMaleMice, Inbred C57BL
Funding
- Agence Nationale de la Recherche
Citations
4,637
FWCI
40.69
field-weighted impact
References
48
Percentile
100%
vs. same field & year
Citations per year
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