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Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss

Diabetes · 2010 · Vol. 59(12) · pp. 3049–3057
Jean‐Pierre FuretLingchun KongJulien TapChristine PoitouArnaud BasdevantJean‐Luc BouillotDenis MariatGérard CorthierJoël DoréCorneliu HénégarSalwa W. RizkallaKarine Clément

Abstract

These results suggest that components of the dominant gut microbiota rapidly adapt in a starvation-like situation induced by RYGB while the F. prausnitzii species is directly linked to the reduction in low-grade inflammation state in obesity and diabetes independently of calorie intake.

Gut microbiota and healthDiet and metabolism studiesBariatric Surgery and OutcomesFaecalibacterium prausnitziiGut floraWeight lossObesityBacteroidesLactobacillusBifidobacteriumDiabetes mellitusVeillonellaBiology

MeSH terms

Adaptation, PhysiologicalBacteroidesBifidobacteriumBlood GlucoseClostridiumEscherichia coliFecesFemaleHumansInflammationLactobacillusLeuconostocMaleObesityPediococcus

Funding

  • American Diabetes Association
  • Sanofi
  • Danone
  • Agence Nationale de la Recherche
  • Institut National de la Recherche Agronomique
  • NIH Clinical Center
  • CHIST-ERA
Citations
1,162
FWCI
20.29
field-weighted impact
References
53
Percentile
100%
vs. same field & year
Citations per year
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References
Obesity alters gut microbial ecology
Proceedings of the National Academy of Sciences · 2005 · 6,096 citations
Towards the human intestinal microbiota phylogenetic core
Environmental Microbiology · 2009 · 888 citations
Human colonic microbiota associated with diet, obesity and weight loss
International Journal of Obesity · 2008 · 1,220 citations
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Nature · 2006 · 8,677 citations
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