article Open AccessTop 1% cited

Intravenous Administration of Human Umbilical Cord Blood Reduces Behavioral Deficits After Stroke in Rats

Stroke · 2001 · Vol. 32(11) · pp. 2682–2688

J Chen✉(Oakland University)Paul R. Sanberg(Oakland University)Y Li(Oakland University)Lei Wang(Oakland University)Mei Lü(Oakland University)A.E. Willing(Oakland University)Juan Sanchez‐Ramos(Oakland University)Michael Chopp(Oakland University)

View via DOI Full-text PDF

Abstract

Intravenously administered HUCBC enter brain, survive, migrate, and improve functional recovery after stroke. HUCBC transplantation may provide a cell source to treat stroke.

Mesenchymal stem cell research Neurogenesis and neuroplasticity mechanisms Neuroinflammation and Neurodegeneration MechanismsMedicineNeuNGlial fibrillary acidic proteinStroke (engine)Umbilical cordAstrocyteAnesthesiaIschemiaPharmacologyInternal medicine

MeSH terms

AnimalsBehavior, AnimalBrainCell DifferentiationCell ExtractsCell SurvivalBrain IschemiaChemotaxisFetal BloodHumansInfusions, IntravenousMaleRats, WistarInfarction, Middle Cerebral ArteryStroke

Citations

1,341

FWCI

14.20

field-weighted impact

References

Percentile

99%

vs. same field & year

Citations per year

Cited by

Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury