reviewTop 1% cited
Vitamin D Deficiency
New England Journal of Medicine · 2007 · Vol. 357(3) · pp. 266–281
Michael F. Holick✉(Boston Medical Center)
Abstract
Once foods in the United States were fortified with vitamin D, rickets appeared to have been conquered, and many considered major health problems from vitamin D deficiency resolved. But vitamin D deficiency is common. This review considers the role of vitamin D in skeletal and nonskeletal health and suggests strategies for the prevention and treatment of vitamin D deficiency.
Vitamin D Research StudiesVitamin C and Antioxidants ResearchBone health and osteoporosis researchMedicineRicketsvitamin D deficiencyVitamin D and neurologyVitaminVitamin deficiencyVitamin A deficiencyEndocrinologyPhysiologyPediatrics
MeSH terms
AdultAgedBone and BonesCalciumChildFemaleHumansKidney Failure, ChronicMaleOsteoporosisPhosphorusVitamin DVitamin D DeficiencyPrevalence
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References
Hypovitaminosis D is associated with insulin resistance and β cell dysfunction
American Journal of Clinical Nutrition · 2004 · 1,623 citations
FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis
Journal of Bone and Mineral Research · 2004 · 1,848 citations
Bone metabolism and disease in chronic kidney disease
American Journal of Kidney Diseases · 2003 · 1,261 citations
High Prevalence of Vitamin D Inadequacy and Implications for Health
Mayo Clinic Proceedings · 2006 · 2,029 citations
Vitamin D regulation of the renin–angiotensin system
Journal of Cellular Biochemistry · 2003 · 362 citations
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes
American Journal of Clinical Nutrition · 2006 · 2,418 citations
Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol
American Journal of Clinical Nutrition · 2003 · 1,408 citations
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