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FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis
Journal of Bone and Mineral Research · 2004 · Vol. 19(3) · pp. 429–435
Takashi ShimadaHisashi HasegawaY. YamazakiTakanori MutoRieko HinoYasuhiro Takeuchi(The University of Tokyo)Toshiro Fujita(The University of Tokyo)Kazuhiko Nakahara(University of Tokyo Hospital)Seiji Fukumoto(University of Tokyo Hospital)Takeyoshi Yamashita✉
Abstract
FGF-23 regulates NaPi-2a independently of PTH and the serum 1,25(OH)2D level by controlling renal expressions of key enzymes of the vitamin D metabolism. In conclusion, FGF-23 is a potent regulator of phosphate and vitamin D homeostasis.
Parathyroid Disorders and TreatmentsVitamin D Research StudiesBone health and treatmentsHypophosphatemiaEndocrinologyInternal medicineFibroblast growth factor 23Parathyroid hormoneVitamin D and neurologyFibroblast growth factorVitaminChemistryHypophosphatemic Rickets
MeSH terms
Fibroblast Growth Factor-23AnimalsFibroblast Growth FactorsHomeostasisMalePhosphatesRecombinant ProteinsTime FactorsVitamin DHypophosphatemiaMiceRats
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References
A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of d-glucose and choline transport systems
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1978 · 1,147 citations
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