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Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research

Journal of Bone and Mineral Research · 2011 · Vol. 26(10) · pp. 2317–2337

John P. Bilezikian✉(Columbia University)Aliya Khan(McMaster University)John T. Potts(Harvard University)Maria Luisa Brandi(University of Florence)B.L. Clarke(Mayo Clinic in Arizona)Dolores Shoback(San Francisco VA Medical Center)Harald Jüppner(Massachusetts General Hospital)P D'Amour(Université de Montréal)John FoxLars Rejnmark(Aarhus University Hospital)Leif Mosekilde(Aarhus University Hospital)Mishaela R. Rubin(Columbia University)David W. Dempster(Helen Hayes Hospital)Rachel I. Gafni(National Institute of Dental and Craniofacial Research)Michael T. Collins(National Institute of Dental and Craniofacial Research)J. Sliney(Columbia University)James M. Sanders

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Abstract

Recent advances in understanding the epidemiology, genetics, diagnosis, clinical presentations, skeletal involvement, and therapeutic approaches to hypoparathyroidism led to the First International Workshop on Hypoparathyroidism that was held in 2009. At this conference, a group of experts convened to discuss these issues with a view towards a future research agenda for this disease. This review, which focuses primarily on hypoparathyroidism in the adult, provides a comprehensive summary of the latest information on this disease.

Thyroid and Parathyroid Surgery Parathyroid Disorders and Treatments Thyroid Cancer Diagnosis and TreatmentHypoparathyroidismEpidemiologyPathophysiologyMedicineIntensive care medicineBioinformaticsPathologyInternal medicineBiology