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Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
BMJ · 2000 · Vol. 321(7258) · pp. 405–412
Irene Stratton✉(University of Oxford)
Abstract
In patients with type 2 diabetes the risk of diabetic complications was strongly associated with previous hyperglycaemia. Any reduction in HbA(1c) is likely to reduce the risk of complications, with the lowest risk being in those with HbA(1c) values in the normal range (<6.0%).
Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and ManagementNatural Antidiabetic Agents StudiesMedicineDiabetes mellitusInternal medicineType 2 diabetesUnited Kingdom Prospective Diabetes StudyMacrovascular diseaseRelative riskMyocardial infarctionIncidence (geometry)Retinopathy
MeSH terms
Cataract ExtractionDiabetes Mellitus, Type 2Diabetic AngiopathiesFemaleHeart FailureGlycated HemoglobinHumansMaleMiddle AgedMyocardial InfarctionProspective StudiesRiskTime FactorsIncidenceMultivariate Analysis
Funding
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- British Heart Foundation
- Novo Nordisk
- National Institutes of Health
- Medical Research Council
- National Eye Institute
Citations
8,937
FWCI
130.12
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
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BMJ · 2000 · 2,144 citations
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
The Lancet · 1998 · 8,242 citations
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