article Open AccessTop 1% cited
Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study
BMJ · 2000 · Vol. 321(7258) · pp. 412–419
Amanda Adler✉(Oxford Centre for Diabetes, Endocrinology and Metabolism)
Abstract
In patients with type 2 diabetes the risk of diabetic complications was strongly associated with raised blood pressure. Any reduction in blood pressure is likely to reduce the risk of complications, with the lowest risk being in those with systolic blood pressure less than 120 mm Hg.
Blood Pressure and Hypertension StudiesPharmacology and Obesity TreatmentDiabetes, Cardiovascular Risks, and LipoproteinsMedicineBlood pressureDiabetes mellitusInternal medicineType 2 diabetesMyocardial infarctionCardiologyStroke (engine)United Kingdom Prospective Diabetes StudyRelative risk
MeSH terms
AdultAgedCataract ExtractionDiabetes Mellitus, Type 2Diabetic AngiopathiesFemaleHeart FailureHumansHypertensionMaleMiddle AgedMyocardial InfarctionProspective StudiesRegression AnalysisRisk
Funding
- Bristol-Myers Squibb
- Eli Lilly and Company
- British Heart Foundation
- Novo Nordisk
- National Institutes of Health
- Medical Research Council
- National Eye Institute
Citations
2,144
FWCI
60.96
field-weighted impact
References
95
Percentile
100%
vs. same field & year
Citations per year
Cited by
Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1)
The Journal of Clinical Endocrinology & Metabolism · 2012 · 1,439 citations
2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD
European Heart Journal · 2019 · 4,808 citations
Diabetic Nephropathy: Diagnosis, Prevention, and Treatment
Diabetes Care · 2005 · 1,821 citations
Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack
Stroke · 2006 · 1,879 citations
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Hypertension · 2017 · 7,315 citations
ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD
European Heart Journal · 2013 · 1,949 citations
Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document
Journal of Hypertension · 2009 · 1,655 citations
2013 ESH/ESC Guidelines for the management of arterial hypertension
European Heart Journal · 2013 · 13,652 citations
References
Hypertension in Diabetes Study (HDS): I. Prevalence of hypertension in newly presenting type 2 diabetic patients and the association with risk factors for cardiovascular and diabetic complications
Journal of Hypertension · 1993 · 494 citations
Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients
New England Journal of Medicine · 2000 · 8,641 citations
Diabetes, Other Risk Factors, and 12-Yr Cardiovascular Mortality for Men Screened in the Multiple Risk Factor Intervention Trial
Diabetes Care · 1993 · 4,087 citations
Diabetes and cardiovascular disease. The Framingham study
JAMA · 1979 · 3,990 citations
Risk factors for myocardial infarction and death in newly detected NIDDM: the Diabetes Intervention Study, 11-year follow-up
Diabetologia · 1996 · 879 citations
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
BMJ · 2000 · 8,937 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.