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Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom prospective diabetes study (UKPDS: 23)

BMJ · 1998 · Vol. 316(7134) · pp. 823–828
R. C. TurnerHelen MillnsH. A. W. NeilIrene StrattonSusan E. ManleyDavid R. MatthewsRury R. Holman

Abstract

A quintet of potentially modifiable risk factors for coronary artery disease exists in patients with type 2 diabetes mellitus. These risk factors are increased concentrations of low density lipoprotein cholesterol, decreased concentrations of high density lipoprotein cholesterol, raised blood pressure, hyperglycaemia, and smoking.

Diabetes, Cardiovascular Risks, and LipoproteinsLipoproteins and Cardiovascular HealthObesity, Physical Activity, DietMedicineInternal medicineCoronary artery diseaseDiabetes mellitusCardiologyHazard ratioBlood pressureMyocardial infarctionAnginaProportional hazards model

MeSH terms

AdultAgedCoronary DiseaseDiabetes Mellitus, Type 2FemaleFollow-Up StudiesUnited KingdomHumansCholesterol, HDLCholesterol, LDLMaleMiddle AgedProspective StudiesRisk FactorsProportional Hazards Models

Funding

  • Bristol-Myers Squibb
  • Eli Lilly and Company
  • British Heart Foundation
  • University of Oxford
  • National Institutes of Health
  • Medical Research Council
  • National Eye Institute
Citations
2,031
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38.99
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