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Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease

Gut · 2004 · Vol. 53(5) · pp. 685–693
S. OttM MusfeldtD F WenderothJ HampeO BrantU R FölschK N TimmisS Schreiber

Abstract

Mucosal inflammation in inflammatory bowel disease is associated with loss of normal anaerobic bacteria. This effect is independent of NOD2/CARD15 status of patients.

Microscopic ColitisInflammatory Bowel DiseaseClostridium difficile and Clostridium perfringens researchInflammatory bowel diseaseIntestinal mucosaMedicineInflammatory Bowel DiseasesUlcerative colitisDiseaseReduction (mathematics)GastroenterologyPathologyMicrobiology

MeSH terms

AdolescentAdultAgedAged, 80 and overBacteriaBacteria, AnaerobicCarrier ProteinsColonCrohn DiseaseFemaleGenotypeHumansIntestinal MucosaMaleMiddle Aged

Funding

  • Crohn's and Colitis Foundation of America
  • Crohn's and Colitis Foundation
  • Deutsche Forschungsgemeinschaft
  • Bundesministerium für Bildung und Forschung
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