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Meta‐analysis: the effect of probiotic administration on antibiotic‐associated diarrhoea
Alimentary Pharmacology & Therapeutics · 2002 · Vol. 16(8) · pp. 1461–1467
Filippo Cremonini✉(Agostino Gemelli University Polyclinic)S. Di(Agostino Gemelli University Polyclinic)E.C. Nista(Agostino Gemelli University Polyclinic)Francesco Bartolozzi(Università Cattolica del Sacro Cuore)Giovanni Capelli(Università Cattolica del Sacro Cuore)Antonio Gasbarrini(Agostino Gemelli University Polyclinic)Antonio Gasbarrini(Agostino Gemelli University Polyclinic)
Abstract
The results suggest a strong benefit of probiotic administration on antibiotic-associated diarrhoea, but further data are needed. The evidence for beneficial effects is still not definitive. Published studies are flawed by the lack of a placebo design and by peculiar population features.
Probiotics and Fermented FoodsGut microbiota and healthClostridium difficile and Clostridium perfringens researchMedicineRelative riskProbioticPlaceboAntibioticsMeta-analysisConfidence intervalPopulationInternal medicineDiarrhea
MeSH terms
Acute DiseaseAdultAgedAnti-Bacterial AgentsAntidiarrhealsDiarrheaHumansMiddle AgedRandomized Controlled Trials as TopicProbiotics
Citations
381
FWCI
35.31
field-weighted impact
References
41
Percentile
100%
vs. same field & year
Citations per year
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