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Meta-Analysis of Probiotics for the Prevention of Antibiotic Associated Diarrhea and the Treatment of Clostridium difficile Disease

The American Journal of Gastroenterology · 2006 · Vol. 101(4) · pp. 812–822
Lynne V. McFarland

Abstract

A variety of different types of probiotics show promise as effective therapies for these two diseases. Using meta-analyses, three types of probiotics (Saccharomyces boulardii, Lactobacillus rhamnosus GG, and probiotic mixtures) significantly reduced the development of antibiotic-associated diarrhea. Only S. boulardii was effective for CDD.

Clostridium difficile and Clostridium perfringens researchProbiotics and Fermented FoodsGut microbiota and healthMedicineInternal medicineClostridium difficileRandomized controlled trialClinical trialAntibiotic-associated diarrheaDiarrheaPopulationRelative riskCochrane Library

MeSH terms

Anti-Bacterial AgentsDiarrheaEnterocolitis, PseudomembranousHumansClostridioides difficileProbiotics
Citations
868
FWCI
31.18
field-weighted impact
References
86
Percentile
100%
vs. same field & year
Citations per year
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