article Open AccessTop 1% cited
Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer
Journal of Clinical Oncology · 2008 · Vol. 26(8) · pp. 1275–1281
Cornelia Liedtke✉(Institut Gustave Roussy)Chafika Mazouni(The University of Texas MD Anderson Cancer Center)Kenneth R. Hess(The University of Texas MD Anderson Cancer Center)Fabrice André(The University of Texas MD Anderson Cancer Center)Attila Tordai(Institut Gustave Roussy)Jaime Mejia(The University of Texas MD Anderson Cancer Center)W. Fraser Symmans(Institut Gustave Roussy)Ana M. González-Angulo(Institut Gustave Roussy)Bryan T. Hennessy(Institut Gustave Roussy)Marjorie Green(Institut Gustave Roussy)Massimo Cristofanilli(Institut Gustave Roussy)Gabriel N. Hortobágyi(Institut Gustave Roussy)Lajos Pusztai(Institut Gustave Roussy)
Abstract
Patients with TNBC have increased pCR rates compared with non-TNBC, and those with pCR have excellent survival. However, patients with RD after neoadjuvant chemotherapy have significantly worse survival if they have TNBC compared with non-TNBC, particularly in the first 3 years.
Breast Cancer Treatment StudiesHER2/EGFR in Cancer ResearchBreast Lesions and CarcinomasMedicineTriple-negative breast cancerBreast cancerOncologyInternal medicineEstrogen receptorNeoadjuvant therapyChemotherapyStage (stratigraphy)Progesterone receptor
MeSH terms
AdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsFemaleHumansMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingNeoplasms, Hormone-DependentPrognosisProspective StudiesReceptors, EstrogenReceptors, Progesterone
Funding
- Breast Cancer Research Foundation
- Hungarian-American Enterprise Scholarship Fund
- Deutsche Forschungsgemeinschaft
- National Cancer Institute
Citations
2,876
FWCI
39.40
field-weighted impact
References
12
Percentile
100%
vs. same field & year
Citations per year
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References
Descriptive analysis of estrogen receptor (ER)‐negative, progesterone receptor (PR)‐negative, and HER2‐negative invasive breast cancer, the so‐called triple‐negative phenotype
Cancer · 2007 · 2,068 citations
The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes
Clinical Cancer Research · 2007 · 2,107 citations
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials
The Lancet · 2005 · 5,095 citations
Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study
JAMA · 2006 · 3,808 citations
Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence
Clinical Cancer Research · 2007 · 5,037 citations
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