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NCBI GEO: archive for functional genomics data sets—update

Nucleic Acids Research · 2012 · Vol. 41(D1) · pp. D991–D995

Tanya Barrett✉(National Center for Biotechnology Information)Stephen E. Wilhite(National Center for Biotechnology Information)Pierre Ledoux(National Institutes of Health)Carlos Evangelista(National Center for Biotechnology Information)Irene F. Kim(National Center for Biotechnology Information)Maxim Tomashevsky(National Cancer Institute)Kimberly A. Marshall(National Cancer Institute)Katherine Phillippy(National Center for Biotechnology Information)Patti M. Sherman(National Center for Biotechnology Information)Michelle Holko(National Institutes of Health)Andrey Yefanov(National Institutes of Health)Hyeseung Lee(National Institutes of Health)Naigong Zhang(National Institutes of Health)C. Robertson(National Center for Biotechnology Information)Nadezhda Serova(National Institutes of Health)Sean Davis(National Institutes of Health)Alexandra Soboleva(National Center for Biotechnology Information)

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Abstract

The Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) is an international public repository for high-throughput microarray and next-generation sequence functional genomic data sets submitted by the research community. The resource supports archiving of raw data, processed data and metadata which are indexed, cross-linked and searchable. All data are freely available for download in a variety of formats. GEO also provides several web-based tools and strategies to assist users to query, analyse and visualize data. This article reports current status and recent database developments, including the release of GEO2R, an R-based web application that helps users analyse GEO data.

Gene expression and cancer classification Bioinformatics and Genomic Networks Genomics and Phylogenetic StudiesMetadataDownloadBiologyRaw dataGenomicsThe InternetResource (disambiguation)Variety (cybernetics)Functional genomicsWorld Wide Web