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Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Nature Methods · 2013 · Vol. 10(12) · pp. 1213–1218
Jason D. BuenrostroPaul G. GiresiLisa C. ZabaHoward Y. ChangWilliam J. Greenleaf
Genomics and Chromatin DynamicsEpigenetics and DNA MethylationImmunotherapy and Immune ResponsesChromatinEpigenomicsNucleosomeTransposaseEpigenomeBiologyChIP-sequencingComputational biologyGeneticsDNA

MeSH terms

Cell SeparationChromatinDNA-Binding ProteinsEnhancer Elements, GeneticFlow CytometryHumansInterleukin-2NucleosomesTranscription FactorsCD4-Positive T-LymphocytesPolymerase Chain ReactionDimerizationComputational BiologyEpigenomics
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References
mRNA-Seq whole-transcriptome analysis of a single cell
Nature Methods · 2009 · 3,942 citations
Cluster analysis and display of genome-wide expression patterns
Proceedings of the National Academy of Sciences · 1998 · 16,353 citations
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Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position · Scinovex