article Open AccessTop 1% cited
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
The EMBO Journal · 2001 · Vol. 20(24) · pp. 6969–6978
Histone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsEpigenetics and DNA MethylationValproic AcidBiologyHistone deacetylaseCancer researchHistoneAcetylationHaematopoiesisCancer cellMyeloid leukemiaIn vivo
MeSH terms
AnimalsCell DifferentiationCell Line, TransformedEnzyme InhibitorsCricetinaeHumansReceptors, GlucocorticoidTranscription FactorsTranscription, GeneticValproic AcidReceptors, Cytoplasmic and NuclearHistone Deacetylase Inhibitors
Funding
- Deutsche Forschungsgemeinschaft
- Associazione Italiana per la Ricerca sul Cancro
- Fondazione Italiana per la Ricerca sul Cancro
Citations
1,871
FWCI
13.66
field-weighted impact
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50
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99%
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References
The language of covalent histone modifications
Nature · 2000 · 8,530 citations
Histone Deacetylase Inhibitors: Inducers of Differentiation or Apoptosis of Transformed Cells
JNCI Journal of the National Cancer Institute · 2000 · 1,162 citations
The coregulator exchange in transcriptional functions of nuclear receptors
Genes & Development · 2000 · 2,228 citations
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