reviewTop 1% cited
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
Nature reviews. Immunology · 2007 · Vol. 7(5) · pp. 353–364
Luke O'neill✉(Trinity College Dublin)Andrew Bowie(Trinity College Dublin)
Immune Response and InflammationNF-κB Signaling PathwaysCytokine Signaling Pathways and InteractionsTRIFSignal transducing adaptor proteinInterferon regulatory factorsTLR2Cell biologyIRF3Toll-like receptorTranscription factorTLR4Receptor
MeSH terms
AnimalsCytoskeletal ProteinsHumansSignal TransductionAdaptor Proteins, Vesicular TransportAdaptor Proteins, Signal TransducingArmadillo Domain ProteinsToll-Like ReceptorsMyeloid Differentiation Factor 88
Funding
- Health Research Board
- Science Foundation Ireland
- Irish Research Council
Citations
2,612
FWCI
62.97
field-weighted impact
References
119
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100%
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References
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Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling
The Journal of Immunology · 2002 · 1,222 citations
Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible to <i>Staphylococcus aureus</i> Infection
The Journal of Immunology · 2000 · 1,046 citations
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