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Associations of Subclinical Cardiovascular Disease With Frailty

The Journals of Gerontology Series A · 2001 · Vol. 56(3) · pp. M158–M166
Anne B. NewmanJohn S. GottdienerMary Ann McBurnieCalvin H. HirschWillem J. KopRussell P. TracyJeremy WalstonLinda P. Fried

Abstract

Cardiovascular disease was associated with an increased likelihood of frail health. In those with no history of CVD, the extent of underlying cardiovascular disease measured by carotid ultrasound and ankle-arm index, LV hypertrophy by ECG and echocardiography, was related to frailty. Infarct-like lesions in the brain on magnet resonance imaging were related to frailty as well.

Frailty in Older AdultsNutrition and Health in AgingCardiovascular Health and Disease PreventionMedicineSubclinical infectionWeight lossHeart failureDiseaseFrailty syndromeCohortOdds ratioInternal medicineConfidence interval

MeSH terms

AgedAnkleArmBlack or African AmericanBlood PressureBrainCardiovascular DiseasesCarotid Artery DiseasesCerebral InfarctionCerebrovascular DisordersEchocardiographyElectrocardiographyHealth StatusHeart FailureHumans

Funding

  • U.S. Department of Defense
  • Wake Forest University
  • University of Washington
  • Johns Hopkins University
  • University of Pittsburgh
  • National Institutes of Health
  • Uniformed Services University of the Health Sciences
  • University of California, Davis
  • University of California, Irvine
  • Claude Pepper Older Americans Independence Center, Wake Forest School of Medicine
  • National Heart, Lung, and Blood Institute
Citations
808
FWCI
14.57
field-weighted impact
References
46
Percentile
99%
vs. same field & year
Citations per year
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