article Open AccessTop 10% cited
Associations of Subclinical Cardiovascular Disease With Frailty
The Journals of Gerontology Series A · 2001 · Vol. 56(3) · pp. M158–M166
Anne B. Newman✉(University of Pittsburgh)John S. Gottdiener(St. Francis Hospital)Mary Ann McBurnie(University of Washington)Calvin H. Hirsch(University of Pittsburgh)Willem J. Kop(Georgetown University)Russell P. Tracy(University of Pittsburgh)Jeremy Walston(University of Pittsburgh)Linda P. Fried(University of Pittsburgh)
Abstract
Cardiovascular disease was associated with an increased likelihood of frail health. In those with no history of CVD, the extent of underlying cardiovascular disease measured by carotid ultrasound and ankle-arm index, LV hypertrophy by ECG and echocardiography, was related to frailty. Infarct-like lesions in the brain on magnet resonance imaging were related to frailty as well.
Frailty in Older AdultsNutrition and Health in AgingCardiovascular Health and Disease PreventionMedicineSubclinical infectionWeight lossHeart failureDiseaseFrailty syndromeCohortOdds ratioInternal medicineConfidence interval
MeSH terms
AgedAnkleArmBlack or African AmericanBlood PressureBrainCardiovascular DiseasesCarotid Artery DiseasesCerebral InfarctionCerebrovascular DisordersEchocardiographyElectrocardiographyHealth StatusHeart FailureHumans
Funding
- U.S. Department of Defense
- Wake Forest University
- University of Washington
- Johns Hopkins University
- University of Pittsburgh
- National Institutes of Health
- Uniformed Services University of the Health Sciences
- University of California, Davis
- University of California, Irvine
- Claude Pepper Older Americans Independence Center, Wake Forest School of Medicine
- National Heart, Lung, and Blood Institute
Citations
808
FWCI
14.57
field-weighted impact
References
46
Percentile
99%
vs. same field & year
Citations per year
Cited by
Transitions Between Frailty States Among Community-Living Older Persons
Archives of Internal Medicine · 2006 · 1,077 citations
Frailty: An Emerging Research and Clinical Paradigm--Issues and Controversies
The Journals of Gerontology Series A · 2007 · 1,128 citations
Endocrine and inflammatory markers as predictors of frailty
Clinical Endocrinology · 2005 · 318 citations
Frailty and Risk of Falls, Fracture, and Mortality in Older Women: The Study of Osteoporotic Fractures
The Journals of Gerontology Series A · 2007 · 762 citations
Silent brain infarcts: a systematic review
The Lancet Neurology · 2007 · 1,199 citations
The prevalence of frailty in heart failure: A systematic review and meta-analysis
International Journal of Cardiology · 2017 · 488 citations
Frailty: Emergence and Consequences in Women Aged 65 and Older in the Women's Health Initiative Observational Study
Journal of the American Geriatrics Society · 2005 · 1,048 citations
Role of Frailty in Patients With Cardiovascular Disease
The American Journal of Cardiology · 2009 · 610 citations
References
Serum IL‐6 Level and the Development of Disability in Older Persons
Journal of the American Geriatrics Society · 1999 · 805 citations
Peripheral Arterial Disease in the Elderly
Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 731 citations
Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings
The American Journal of Cardiology · 1986 · 6,215 citations
Ankle-Arm Index as a Predictor of Cardiovascular Disease and Mortality in the Cardiovascular Health Study
Arteriosclerosis Thrombosis and Vascular Biology · 1999 · 873 citations
Associations of elevated Interleukin-6 and C-Reactive protein levels with mortality in the elderly
The American Journal of Medicine · 1999 · 1,479 citations
Clinical Correlates of White Matter Findings on Cranial Magnetic Resonance Imaging of 3301 Elderly People
Stroke · 1996 · 1,468 citations
Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.
Circulation · 1978 · 7,465 citations
Association of Coronary Heart Disease Incidence with Carotid Arterial Wall Thickness and Major Risk Factors: The Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993
American Journal of Epidemiology · 1997 · 1,999 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
