articleTop 1% cited

Clinical Correlates of White Matter Findings on Cranial Magnetic Resonance Imaging of 3301 Elderly People

Stroke · 1996 · Vol. 27(8) · pp. 1274–1282

W. T. Longstreth✉(University of Arizona)Teri A. Manolio(Neurological Surgery)Alice M. Arnold(Johns Hopkins University)Gregory L. Burke(Johns Hopkins University)Nick Bryan(Johns Hopkins Medicine)Charles A. Jungreis(Johns Hopkins University)Paul Enright(University of Arizona)Daniel E. O’Leary(Neurological Surgery)Linda P. Fried(National Heart Lung and Blood Institute)

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Abstract

White matter findings were significantly associated with age, silent stroke, hypertension, FEV1, and income. The white matter findings may not be considered benign because they are associated with impaired cognitive and lower extremity function.

Cardiovascular Health and Disease Prevention Cerebrovascular and Carotid Artery Diseases Cardiovascular Disease and AdiposityMedicineWhite matterStroke (engine)Magnetic resonance imagingPhysical examinationInternal medicineLeukoaraiosisMedical historyHyperintensityYoung adult

MeSH terms

Age FactorsAgedAgingBlood PressureBrainCardiovascular DiseasesIschemic Attack, TransientCerebrovascular DisordersFemaleHumansMagnetic Resonance ImagingMaleRisk FactorsSex FactorsCohort Studies

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2018 ESC/ESH Guidelines for the management of arterial hypertension