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ω-3 Fatty Acid Treatment in 174 Patients With Mild to Moderate Alzheimer Disease: OmegAD Study

Archives of Neurology · 2006 · Vol. 63(10) · pp. 1402–1402

Yvonne Freund‐Levi✉(Karolinska University Hospital)Maria EriksdotterTommy CederholmHans BasunGerd Faxén IrvingAnita GarlindInger VedinBengt VessbyLars‐Olof WahlundJan Palmblad

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Abstract

Administration of omega-3 fatty acid in patients with mild to moderate AD did not delay the rate of cognitive decline according to the MMSE or the cognitive portion of the Alzheimer Disease Assessment Scale. However, positive effects were observed in a small group of patients with very mild AD (MMSE >27 points).

Fatty Acid Research and Health Folate and B Vitamins Research Diet and metabolism studiesDocosahexaenoic acidEicosapentaenoic acidTolerabilityInternal medicineDementiaGastroenterologyFish oilPlaceboMedicineMini–Mental State Examination

MeSH terms

AgedAlzheimer DiseaseBlood PressureBrainCognition DisordersDouble-Blind MethodFemaleHumansMaleMiddle AgedFatty Acids, Omega-3Placebo EffectTreatment OutcomeDisease ProgressionNeuroprotective Agents

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Defeating Alzheimer's disease and other dementias: a priority for European science and society