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The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints

Molecular Pharmacology · 2003 · Vol. 63(6) · pp. 1256–1272
Robert FredrikssonMalin C. LagerströmLars‐Gustav LundinHelgi B. Schiöth
Receptor Mechanisms and SignalingMachine Learning in BioinformaticsBiochemical Analysis and Sensing TechniquesG protein-coupled receptorBiologyGenomeComputational biologyHuman genomePhylogenetic treeGeneticsRhodopsinPhylogenetic nomenclatureGene duplication

MeSH terms

Chromosome MappingHumansMembrane GlycoproteinsMembrane ProteinsPhylogenyReceptors, Cell SurfaceReceptors, Gastrointestinal HormoneRhodopsinGenome, HumanSequence Homology, Amino AcidReceptors, GlutamatePlatelet Glycoprotein GPIb-IX ComplexGTP-Binding ProteinsSequence Analysis, ProteinReceptors, G-Protein-Coupled

Funding

  • University of California, Santa Cruz
  • University of Edinburgh
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The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints · Scinovex