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IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells
Immunity · 2002 · Vol. 16(6) · pp. 779–790
Stefan Pflanz(Genetic Information Research Institute)Jackie C. Timans(Genetic Information Research Institute)Jeanne Cheung(Genetic Information Research Institute)Rency Rosales(Genetic Information Research Institute)Holger Kanzler(Genetic Information Research Institute)Jonathan B. Gilbert(Genetic Information Research Institute)Linda Hibbert(Genetic Information Research Institute)Tatyana Churakova(Genetic Information Research Institute)Marilyn Travis(Genetic Information Research Institute)Elena Vaisberg(Genetic Information Research Institute)Wendy M. Blumenschein(Genetic Information Research Institute)Jeanine Mattson(Genetic Information Research Institute)Janet Wagner(Genetic Information Research Institute)Wayne To(Genetic Information Research Institute)Sandra Zurawski(Genetic Information Research Institute)Terrill K. McClanahan(Genetic Information Research Institute)Daniel M. Gorman(Genetic Information Research Institute)J. Fernando Bazán(Genetic Information Research Institute)René de Waal Malefyt(Genetic Information Research Institute)D Rennick(Genetic Information Research Institute)Robert A. Kastelein✉(Genetic Information Research Institute)
Immune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesBiologyInterleukin 21CytokineCell biologyCD28Interleukin 12T cellAntigen-presenting cellImmune systemZAP70
MeSH terms
Amino Acid SequenceAntigen-Presenting CellsCarrier ProteinsCell DivisionGlutathione TransferaseGlycoproteinsInterferon-gammaInterleukinsMolecular Sequence DataProtein ConformationCD4-Positive T-LymphocytesMinor Histocompatibility AntigensSequence AlignmentReceptors, CytokineReceptors, Interleukin
Funding
- Schering-Plough
Citations
1,454
FWCI
15.68
field-weighted impact
References
35
Percentile
99%
vs. same field & year
Citations per year
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References
Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12
Immunity · 2000 · 2,788 citations
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Nucleic Acids Research · 1997 · 39,127 citations
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
Nucleic Acids Research · 1994 · 64,626 citations
Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity
Annual Review of Immunology · 1995 · 2,419 citations
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
The Journal of Experimental Medicine · 1994 · 5,139 citations
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