article Open AccessTop 10% cited
The use of fractional polynomials to model continuous risk variables in epidemiology
International Journal of Epidemiology · 1999 · Vol. 28(5) · pp. 964–974
Patrick Royston✉(Imperial College London)Gareth Ambler(Imperial College London)Willi Sauerbrei(University of Freiburg)
Abstract
Our approach based on fractional polynomials should be considered as an important alternative to the traditional approaches for the analysis of continuous variables in epidemiological studies.
Diverse Scientific and Engineering ResearchAdvanced Statistical Methods and ModelsCategorizationConfoundingGeneralized linear modelEconometricsLog-linear modelOrdinal regressionMathematicsRegression analysisLinear modelLinear regression
MeSH terms
Coronary DiseaseCross-Sectional StudiesEpidemiologic MethodsUnited KingdomHumansMaleModels, CardiovascularMortalityNeoplasmsProspective StudiesRisk FactorsSensitivity and SpecificityLinear ModelsOdds RatioRisk Assessment
Funding
- Wellcome Trust
Citations
1,076
FWCI
10.63
field-weighted impact
References
50
Percentile
99%
vs. same field & year
Citations per year
Cited by
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration
Annals of Internal Medicine · 2007 · 3,466 citations
Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study
BMJ · 2017 · 1,644 citations
Multi-Ethnic Study of Atherosclerosis: Objectives and Design
American Journal of Epidemiology · 2002 · 3,896 citations
Body mass index and survival in women with breast cancer—systematic literature review and meta-analysis of 82 follow-up studies
Annals of Oncology · 2014 · 1,145 citations
Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock*
Critical Care Medicine · 2009 · 1,012 citations
A meta-analysis of alcohol consumption and the risk of 15 diseases
Preventive Medicine · 2004 · 1,095 citations
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration
PLoS Medicine · 2007 · 8,236 citations
Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction
Journal of the American College of Cardiology · 2013 · 1,767 citations
References
Statistical methods in cancer research. Vol. 1. The analysis of case-control studies
Food and Chemical Toxicology · 1983 · 1,725 citations
RE:“;THE IMPACT OF CONFOUNDER SELECTION CRITERIA ON EFFECT ESTIMATION”
American Journal of Epidemiology · 1989 · 2,121 citations
Applied logistic regression
Choice Reviews Online · 1990 · 35,647 citations
Model Selection: An Integral Part of Inference
Biometrics · 1997 · 1,710 citations
Dangers of Using "Optimal" Cutpoints in the Evaluation of Prognostic Factors
JNCI Journal of the National Cancer Institute · 1994 · 1,124 citations
A COMPARISON OF GOODNESS-OF-FIT TESTS FOR THE LOGISTIC REGRESSION MODEL
Statistics in Medicine · 1997 · 1,831 citations
Generalized Additive Models.
Biometrics · 1991 · 8,286 citations
Generalized Additive Models.
Journal of the American Statistical Association · 1991 · 7,687 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.