article Open AccessTop 1% cited
Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families
The American Journal of Human Genetics · 1998 · Vol. 62(3) · pp. 676–689
Deborah Ford(Institute of Cancer Research)Douglas F. Easton✉Michael R. Stratton(Institute of Cancer Research)Steven A. Narod(Coalition for Research in Women's Health)David E. Goldgar(Centre international de recherche sur le cancer)Peter Devilee(Leiden University)D. Timothy Bishop(University of Leeds)Barbara Weber(University of Pennsylvania)Gilbert Lenoir(Centre international de recherche sur le cancer)Jenny Chang‐Claude(German Cancer Research Center)Hagay Sobol(Inserm)M. Dawn TeareJeffery P. StruewingAðalgeir ArasonSiegfried Scherneck(Max Delbrück Center)Julian Peto(Sutton Hospital)Timothy R. Rebbeck(University of Pennsylvania)Patricia N. Tonin(McGill University)Susan L. Neuhausen(University of Utah)Rósa B. BarkardóttirJórunn E. Eyfjörd(Icelandic Cancer Society)H. Lynch(Creighton University)Bruce A.J. Ponder(University of Cambridge)Simon A. Gayther(University of Cambridge)J.M. Birch(Cancer Research UK Manchester Institute)Annika Lindblom(Karolinska Institutet)Dominique Stoppa‐Lyonnet(Expression Génétique Microbienne)Y.-J. Bignon(Centre Jean Perrin)Åke Borg(Lund University)Ute Hamann(German Cancer Research Center)N E Haites(Kantonsspital Baselland)Rodney J. ScottC.M. MaugardHans F. A. VasenSusanne Seitz(Max Delbrück Center)Lisa Cannon‐Albright(University of Utah)Andrew Craig Schofield(Kantonsspital Baselland)M Zelada-Hedman(Karolinska Institutet)
BRCA gene mutations in cancerCancer Genomics and DiagnosticsOvarian cancer diagnosis and treatmentPenetranceBreast cancerOvarian cancerOncologyCancerGeneticsBiologyBRCA2 ProteinGenetic counselingInternal medicine
MeSH terms
AdultAgedBreast NeoplasmsFemaleGenetic Carrier ScreeningHumansMaleMiddle AgedMutationNeoplasm ProteinsTranscription FactorsGenetic HeterogeneityGenes, BRCA1Genetic Predisposition to DiseaseBRCA2 Protein
Funding
- National Institutes of Health
Citations
3,035
FWCI
82.89
field-weighted impact
References
50
Percentile
100%
vs. same field & year
Citations per year
Cited by
Effects of Age on the Detection and Management of Breast Cancer
Cancers · 2015 · 374 citations
A breast cancer prediction model incorporating familial and personal risk factors
Statistics in Medicine · 2004 · 1,343 citations
Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers
Gynecologic Oncology · 2005 · 375 citations
Male breast cancer: a disease distinct from female breast cancer
Breast Cancer Research and Treatment · 2018 · 372 citations
Cancer Risks in BRCA2 Mutation Carriers
JNCI Journal of the National Cancer Institute · 1999 · 1,521 citations
Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies
The American Journal of Human Genetics · 2003 · 3,661 citations
Prevalence and Penetrance of Germline BRCA1 and BRCA2 Mutations in a Population Series of 649 Women with Ovarian Cancer
The American Journal of Human Genetics · 2001 · 992 citations
Practice Bulletin No. 183: Postpartum Hemorrhage
Obstetrics and Gynecology · 2017 · 1,305 citations
References
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
Nature Genetics · 1997 · 2,083 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.