article Open AccessTop 1% cited
Prevalence and Penetrance of Germline BRCA1 and BRCA2 Mutations in a Population Series of 649 Women with Ovarian Cancer
The American Journal of Human Genetics · 2001 · Vol. 68(3) · pp. 700–710
Harvey A. Risch✉(Yale University)Esther M. John(Toronto Public Health)David E.C. ColeBarry P. RosenLinda BradleyElaine Kwan(Women's College Hospital)Elaine Jack(Women's College Hospital)Danny Vesprini(Women's College Hospital)Graciela Kuperstein(Women's College Hospital)John Abrahamson(Women's College Hospital)Isabel Fan(Women's College Hospital)Betty WongSteven A. Narod(Toronto Public Health)
BRCA gene mutations in cancerOvarian cancer diagnosis and treatmentGenetic factors in colorectal cancerPenetranceOvarian cancerMedicineCancerGermline mutationOncologyFirst-degree relativesBreast cancerPopulationInternal medicine
MeSH terms
Breast NeoplasmsEthnicityFamilyFemaleHumansMaleNeoplasm ProteinsNeoplasmsOntarioOvarian NeoplasmsRisk FactorsTranscription FactorsIncidenceGerm-Line MutationGenes, BRCA1
Funding
- National Cancer Institute
Citations
992
FWCI
29.74
field-weighted impact
References
53
Percentile
100%
vs. same field & year
Citations per year
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References
Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families
The American Journal of Human Genetics · 1998 · 3,035 citations
Cancer Risks in BRCA2 Mutation Carriers
JNCI Journal of the National Cancer Institute · 1999 · 1,521 citations
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