review Open AccessTop 1% cited
Body weight loss reverts obesity-associated hypogonadotropic hypogonadism: a systematic review and meta-analysis
European Journal of Endocrinology · 2013 · Vol. 168(6) · pp. 829–843
Giovanni Corona(University of Florence)Giulia Rastrelli(University of Florence)Matteo Monami(University of Florence)Farid Saad(Bayer (Germany))Michaela Luconi(University of Florence)Marcello Lucchese(University of Florence)Enrico Facchiano(University of Florence)Alessandra Sforza(Azienda USL di Bologna)Gianni Forti(University of Florence)Edoardo Mannucci(Azienda Ospedaliero-Universitaria Careggi)Mario Maggi✉(University of Florence)
Abstract
These data show that weight loss is associated with an increase in both bound and unbound testosterone levels. The normalization of sex hormones induced by body weight loss is a possible mechanism contributing to the beneficial effects of surgery in morbid obesity.
Hormonal and reproductive studiesEating Disorders and BehaviorsMuscle metabolism and nutritionHypogonadotropic hypogonadismEndocrinologyInternal medicineMeta-analysisObesityMedicineHormone
MeSH terms
Body WeightHumansHypogonadismObesityWeight Loss
Citations
402
FWCI
20.76
field-weighted impact
References
72
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100%
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New England Journal of Medicine · 2002 · 18,892 citations
Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study
European Journal of Endocrinology · 2011 · 433 citations
Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle among Subjects with Impaired Glucose Tolerance
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