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Statistical image reconstruction for polyenergetic X-ray computed tomography

IEEE Transactions on Medical Imaging · 2002 · Vol. 21(2) · pp. 89–99
I ElbakriJeffrey A. Fessler

Abstract

This paper describes a statistical image reconstruction method for X-ray computed tomography (CT) that is based on a physical model that accounts for the polyenergetic X-ray source spectrum and the measurement nonlinearities caused by energy-dependent attenuation. We assume that the object consists of a given number of nonoverlapping materials, such as soft tissue and bone. The attenuation coefficient of each voxel is the product of its unknown density and a known energy-dependent mass attenuation coefficient. We formulate a penalized-likelihood function for this polyenergetic model and develop an ordered-subsets iterative algorithm for estimating the unknown densities in each voxel. The algorithm monotonically decreases the cost function at each iteration when one subset is used. Applying this method to simulated X-ray CT measurements of objects containing both bone and soft tissue yields images with significantly reduced beam hardening artifacts.

Advanced X-ray and CT ImagingMedical Imaging Techniques and ApplicationsRadiation Dose and ImagingVoxelIterative reconstructionAttenuationAttenuation coefficientTomographyIterative methodEnergy (signal processing)Computer scienceAlgorithmArtificial intelligence

MeSH terms

AlgorithmsBone and BonesComputer SimulationHumansImage Processing, Computer-AssistedModels, BiologicalMonte Carlo MethodSensitivity and SpecificityTomography, X-Ray ComputedWaterModels, StatisticalPhantoms, Imaging

Funding

  • National Institutes of Health
Citations
685
FWCI
8.22
field-weighted impact
References
45
Percentile
98%
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References
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Beam hardening in X-ray reconstructive tomography
Physics in Medicine and Biology · 1976 · 588 citations
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IEEE Transactions on Medical Imaging · 1994 · 3,675 citations
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Medical Physics · 2002 · 1,886 citations
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