reviewTop 1% cited
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
Angewandte Chemie International Edition · 2012 · Vol. 51(36) · pp. 8960–9009
Junichiro Yamaguchi✉(Nagoya University)Atsushi Yamaguchi(Nagoya University)Kenichiro Itami(Nagoya University)
Abstract
The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
Catalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsAsymmetric Synthesis and CatalysisSurface modificationChemistryCombinatorial chemistryCarbon fibersHeteroatomOrganic chemistryNanotechnologyMaterials scienceRing (chemistry)
MeSH terms
AlkylationBiological ProductsCarbonCatalysisPharmaceutical PreparationsHydrogenIminesMetalsMethaneStereoisomerism
Citations
2,943
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