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Autoxidation versus Covalent Binding of Quinones as the Mechanism of Toxicity of Dopamine, 6-Hydroxydopamine, and Related Compounds toward C1300 Neuroblastoma Cells in Vitro

Molecular Pharmacology · 1978 · Vol. 14(4) · pp. 644–653
Doyle G. GrahamS M TiffanyWilliam R. BellW. F. Gutknecht
Bioactive Compounds and Antitumor AgentsCancer therapeutics and mechanismsOxidative Organic Chemistry ReactionsAutoxidationChemistryCytotoxicityHydroxydopamineQuinoneBiochemistryAdrenochromePolyphenolStereochemistryDopamine

MeSH terms

AnimalsCattleCells, CulturedDopamineHydroxydopaminesNeuroblastomaOxidation-ReductionPhenolsQuinonesThymidineNucleic Acid Synthesis Inhibitors
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