reviewTop 1% cited

Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

Experimental Neurology · 2005 · Vol. 193(2) · pp. 279–290

Andreas Hald(University of Copenhagen)Julie Lotharius✉(Lundbeck (Denmark))

Parkinson's Disease Mechanisms and Treatments Neuroinflammation and Neurodegeneration Mechanisms Nerve injury and regenerationSubstantia nigraDopamineMicrogliaDopaminergicOxidative stressMPTPParkinson's diseaseInflammationParkinsonismNeuroscience

MeSH terms

AnimalsAnti-Inflammatory AgentsDisease Models, AnimalDopamineEncephalitisHumansMitochondriaModels, NeurologicalParkinson DiseaseMicrogliaOxidative Stress

Funding

H. Lundbeck A/S

Citations

505

FWCI

22.43

field-weighted impact

References

138

Percentile

100%

vs. same field & year

Citations per year

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References

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Journal of Neurochemistry · 1999 · 661 citations

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

American Journal of Physiology-Cell Physiology · 1996 · 5,497 citations

Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

Neuroscience Letters · 1994 · 857 citations

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

Neurology · 1988 · 2,969 citations

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

Neuroscience Letters · 1992 · 579 citations

Increased Nigral Iron Content and Alterations in Other Metal Ions Occurring in Brain in Parkinson's Disease

Journal of Neurochemistry · 1989 · 1,141 citations

Cytotoxic and genotoxic potential of dopamine

Journal of Neuroscience Research · 1999 · 476 citations

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