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Effects of testosterone on body composition, bone metabolism and serum lipid profile in middle‐aged men: a meta‐analysis

Clinical Endocrinology · 2005 · Vol. 63(3) · pp. 280–293

Andrea M. Isidori(Sapienza University of Rome)Andrea M. Isidori✉(Sapienza University of Rome)Elisa GiannettaEmanuela A. GrecoDaniele GianfrilliVincenzo BonifacioAldo Isidori✉(Sapienza University of Rome)Aldo Isidori(University of Rome Tor Vergata)Andrea Lenzi(Sapienza University of Rome)Andrea Fabbri(University of Rome Tor Vergata)

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Abstract

The present analysis provides an estimate of the average treatment effects of testosterone therapy in middle-aged men. Our findings are sufficiently strong to justify further interventional studies focused on alternative targets of androgenic treatment carrying more stringent clinical implications, in particular the cardiovascular, metabolic and neurological systems.

Hormonal and reproductive studies Muscle metabolism and nutrition Sexual Differentiation and DisordersMedicineTestosterone (patch)Internal medicineEndocrinologyPlaceboRandomized controlled trialBone remodelingSarcopeniaCochrane LibraryAndrogen

MeSH terms

AdultAgedBody CompositionBone ResorptionData CollectionData Interpretation, StatisticalHumansLipidsMaleMiddle AgedMuscle ContractionTestosteroneBiomarkersBone DensityRandomized Controlled Trials as Topic

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Cited by

Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study