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Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction

Clinical Endocrinology · 2003 · Vol. 58(5) · pp. 632–638

Antônio Aversa✉(Azienda Ospedaliera Fatebenefratelli e Oftalmico)Andrea M. IsidoriGiovanni SperaAndrea Lenzi(Sapienza University of Rome)Andrea Fabbri(University of Rome Tor Vergata)

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Abstract

In patients with arteriogenic ED and low-normal androgen levels, short-term testosterone administration increases T and FT levels and improves the erectile response to sildenafil likely by increasing arterial inflow to the penis during sexual stimulation.

Sexual function and dysfunction studies Sexuality, Behavior, and Technology Hormonal and reproductive studiesErectile dysfunctionMedicineSildenafilInternal medicineTestosterone (patch)EndocrinologyPlaceboUrologyTadalafilAndrogen

MeSH terms

Sildenafil CitrateAgedAndrogensArteriesHumansMaleMiddle AgedPenile ErectionPenisPilot ProjectsPiperazinesProspective StudiesPurinesRegional Blood FlowSulfones