reviewTop 10% cited
The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2010 · Vol. 1807(6) · pp. 568–576
Rodrigo Díaz-Ruiz(Ludwig Cancer Research)Michel Rigoulet(Centre National de la Recherche Scientifique)Anne Devin✉(Centre National de la Recherche Scientifique)
Cancer, Hypoxia, and MetabolismATP Synthase and ATPases ResearchMitochondrial Function and PathologyWarburg effectGlycolysisAnaerobic glycolysisOxidative phosphorylationCancer cellBiologyCancerBioenergeticsCell biologyMitochondrion
MeSH terms
AnimalsCellsEnergy MetabolismBiological EvolutionGlucoseHumansModels, BiologicalModels, TheoreticalNeoplasmsYeastsDown-RegulationGene Expression Regulation, Fungal
Citations
484
FWCI
6.21
field-weighted impact
References
147
Percentile
96%
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Citations per year
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References
Observations on the carbohydrate metabolism of tumours
Biochemical Journal · 1929 · 847 citations
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
Journal of Cellular Physiology · 2004 · 1,237 citations
Cancer genes and the pathways they control
Nature Medicine · 2004 · 4,243 citations
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
Cell Metabolism · 2006 · 2,210 citations
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
Cell Metabolism · 2006 · 3,827 citations
On the Origin of Cancer Cells
Science · 1956 · 13,149 citations
Glycolysis inhibition for anticancer treatment
Oncogene · 2006 · 1,500 citations
Why do cancers have high aerobic glycolysis?
Nature reviews. Cancer · 2004 · 4,733 citations
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