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Early Coagulopathy Predicts Mortality in Trauma

Abstract

The incidence of coagulation abnormalities, early after trauma, is high and they are independent predictors of mortality even in the presence of other risk factors. An initial abnormal PT increases the adjusted odds of dying by 35% and an initial abnormal PTT increases the adjusted odds of dying by 326%.

Trauma and Emergency Care StudiesTrauma, Hemostasis, Coagulopathy, ResuscitationAbdominal Trauma and InjuriesMedicineCoagulopathyConfidence intervalInternal medicineOdds ratioUnivariate analysisPartial thromboplastin timeCohortInjury Severity ScoreProthrombin time

MeSH terms

AdultBlood Coagulation DisordersFemaleHumansMalePartial Thromboplastin TimePredictive Value of TestsProspective StudiesProthrombin TimeRegistriesTrauma CentersWounds and InjuriesLogistic ModelsSurvival Analysis
Citations
1,225
FWCI
17.15
field-weighted impact
References
25
Percentile
99%
vs. same field & year
Citations per year
References
Recombinant Activated Factor VII for Adjunctive Hemorrhage Control in Trauma
The Journal of Trauma: Injury, Infection, and Critical Care · 2001 · 448 citations
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