articleTop 1% cited
Recombinant Activated Factor VII for Adjunctive Hemorrhage Control in Trauma
The Journal of Trauma: Injury, Infection, and Critical Care · 2001 · Vol. 51(3) · pp. 431–439
U. Martinowitz✉(Sheba Medical Center)Gili KenetEran SegalJacob LuboshitzAharon LubetskyJørgen IngerslevMauricio Lynn
Abstract
The results of this report suggest that in trauma patients rFVIIa may play a role as an adjunctive hemostatic measure, in addition to surgical hemostatic techniques, and provides the motivation for controlled animal and clinical trials.
Trauma, Hemostasis, Coagulopathy, ResuscitationHemophilia Treatment and ResearchHemostasis and retained surgical itemsMedicineContraindicationHemostasisPartial thromboplastin timeBleedProthrombin timeAnesthesiaCoagulopathyRecombinant factor VIIaFactor VII
MeSH terms
AdolescentAdultAgedFactor VIIFemaleHemorrhageHemostasisHumansMaleMiddle AgedPartial Thromboplastin TimeProthrombin TimeRecombinant ProteinsWounds and InjuriesFactor VIIa
Citations
448
FWCI
33.18
field-weighted impact
References
53
Percentile
100%
vs. same field & year
Citations per year
Cited by
Management of bleeding following major trauma: an updated European guideline
Critical Care · 2010 · 814 citations
Management of bleeding and coagulopathy following major trauma: an updated European guideline
Critical Care · 2013 · 959 citations
Trauma Associated Severe Hemorrhage (TASH)-Score: Probability of Mass Transfusion as Surrogate for Life Threatening Hemorrhage after Multiple Trauma
The Journal of Trauma: Injury, Infection, and Critical Care · 2006 · 440 citations
Early Coagulopathy Predicts Mortality in Trauma
The Journal of Trauma: Injury, Infection, and Critical Care · 2003 · 1,225 citations
The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition
Critical Care · 2019 · 1,270 citations
The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition
Critical Care · 2016 · 1,474 citations
The Effect of Temperature and pH on the Activity of Factor VIIa: Implications for the Efficacy of High-Dose Factor VIIa in Hypothermic and Acidotic Patients
The Journal of Trauma: Injury, Infection, and Critical Care · 2003 · 471 citations
Recombinant Factor VIIa as Adjunctive Therapy for Bleeding Control in Severely Injured Trauma Patients: Two Parallel Randomized, Placebo-Controlled, Double-Blind Clinical Trials
The Journal of Trauma: Injury, Infection, and Critical Care · 2005 · 782 citations
References
Platelet activity of high‐dose factor VIIa is independent of tissue factor
British Journal of Haematology · 1997 · 538 citations
Prospective, Randomised Trial of Two Doses of rFVIIa (NovoSeven) in Haemophilia Patients with Inhibitors Undergoing Surgery
Thrombosis and Haemostasis · 1998 · 372 citations
The Tissue Factor Pathway: How It Has Become a “Prima Ballerina”
Thrombosis and Haemostasis · 1995 · 406 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.