article Open AccessTop 10% cited
The Bax/Bcl-2 Ratio Determines the Susceptibility of Human Melanoma Cells to CD95/Fas-Mediated Apoptosis
Journal of Investigative Dermatology · 2001 · Vol. 117(2) · pp. 333–340
Monika Raisova(University Medical Center)Amir M. Hossini(University Medical Center)Jürgen Eberle(University Medical Center)Christian Riebeling(University Medical Center)Constantin E. Orfanos(University Medical Center)Christoph C. Geilen✉(University Medical Center)Thomas Wieder(Humboldt-Universität zu Berlin)Isrid Sturm(Humboldt-Universität zu Berlin)Peter T. Daniel(Humboldt-Universität zu Berlin)
Cell death mechanisms and regulationNF-κB Signaling Pathwaysinterferon and immune responsesFas receptorApoptosisMelanomaCancer researchChemistryBiologyProgrammed cell deathGenetics
MeSH terms
Betulinic AcidAntineoplastic Agents, PhytogenicCeramidesCytochrome c GroupDensitometryDNA Mutational AnalysisHumansMelanomaMitochondriaProto-Oncogene ProteinsSkin NeoplasmsTriterpenesTumor Cells, CulturedBlotting, WesternGene Expression Regulation, Neoplastic
Citations
561
FWCI
5.55
field-weighted impact
References
54
Percentile
97%
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Citations per year
References
Mechanisms and consequences of activation of protein kinase B/Akt
Current Opinion in Cell Biology · 1998 · 1,306 citations
Bcl-2 and the regulation of programmed cell death
The Journal of Cell Biology · 1994 · 2,332 citations
In Vitro Cultivation of Human Tumors: Establishment of Cell Lines Derived From a Series of Solid Tumors2
JNCI Journal of the National Cancer Institute · 1973 · 2,301 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
Cell · 1996 · 5,154 citations
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