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Nanoparticles in Medicine: Therapeutic Applications and Developments

Clinical Pharmacology & Therapeutics · 2007 · Vol. 83(5) · pp. 761–769
Luxian ZhangFrank GuJuliana M. ChanAndrew Z. WangLanger RsOmid C. Farokhzad

Abstract

Nanotechnology is the understanding and control of matter generally in the 1-100 nm dimension range. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. Nanomaterials have unique physicochemical properties, such as ultra small size, large surface area to mass ratio, and high reactivity, which are different from bulk materials of the same composition. These properties can be used to overcome some of the limitations found in traditional therapeutic and diagnostic agents.

Nanoparticle-Based Drug DeliveryGold and Silver Nanoparticles Synthesis and ApplicationsGraphene and Nanomaterials ApplicationsNanomedicineNanotechnologyTherapeutic modalitiesNanoparticleNanomaterialsModalitiesMaterials scienceMedicineInternal medicine

MeSH terms

HumansDrug Delivery SystemsNanotechnologyNanoparticles

Funding

  • National Institutes of Health
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References
Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery
Journal of Controlled Release · 2002 · 1,431 citations
Micellar Nanocarriers: Pharmaceutical Perspectives
Pharmaceutical Research · 2006 · 1,853 citations
Recent advances with liposomes as pharmaceutical carriers
Nature Reviews Drug Discovery · 2005 · 5,121 citations
Nanoparticle and targeted systems for cancer therapy
Advanced Drug Delivery Reviews · 2004 · 2,323 citations
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