articleTop 1% cited
Nanoparticles in Medicine: Therapeutic Applications and Developments
Clinical Pharmacology & Therapeutics · 2007 · Vol. 83(5) · pp. 761–769
Luxian Zhang(Massachusetts Institute of Technology)Frank Gu(Massachusetts Institute of Technology)Juliana M. Chan(Massachusetts Institute of Technology)Andrew Z. Wang(Harvard University)Langer Rs(Massachusetts Institute of Technology)Omid C. Farokhzad✉(Brigham and Women's Hospital)
Abstract
Nanotechnology is the understanding and control of matter generally in the 1-100 nm dimension range. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. Nanomaterials have unique physicochemical properties, such as ultra small size, large surface area to mass ratio, and high reactivity, which are different from bulk materials of the same composition. These properties can be used to overcome some of the limitations found in traditional therapeutic and diagnostic agents.
Nanoparticle-Based Drug DeliveryGold and Silver Nanoparticles Synthesis and ApplicationsGraphene and Nanomaterials ApplicationsNanomedicineNanotechnologyTherapeutic modalitiesNanoparticleNanomaterialsModalitiesMaterials scienceMedicineInternal medicine
MeSH terms
HumansDrug Delivery SystemsNanotechnologyNanoparticles
Funding
- National Institutes of Health
Citations
2,584
FWCI
30.86
field-weighted impact
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50
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