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Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria
The American Journal of Gastroenterology · 2010 · Vol. 105(11) · pp. 2420–2428
Chin Wen Png(University of Queensland)Sara K. Lindén(Mater Health Services)Kristen Gilshenan(Mater Research)Erwin G. Zoetendal(Wageningen University & Research)Christopher S. McSweeney(Commonwealth Scientific and Industrial Research Organisation)Lindsay I. Sly(University of Queensland)Michael A. McGuckin(Mater Health Services)Timothy H. Florin✉(University of Queensland)
Abstract
Mucolytic bacteria are present in healthy humans, where they are an integral part of the mucosa-associated bacterial consortium. The disproportionate increase in R. gnavus and R. torques could explain increased total mucosa-associated bacteria in IBD.
Gut microbiota and healthInflammatory Bowel DiseaseMycobacterium research and diagnosisBacteriaMicrobiologyRuminococcusMucinIntestinal mucosaAnaerobic bacteriaMucusMedicineUlcerative colitisBiology
MeSH terms
AdultAgedAged, 80 and overColonFemaleHumansIntestinal MucosaMaleMiddle AgedMucinsInflammatory Bowel DiseasesReverse Transcriptase Polymerase Chain ReactionRuminococcus
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