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The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

Nature Cell Biology · 2000 · Vol. 2(2) · pp. 76–83

Amparo Cano✉(Instituto de Investigaciones Biomédicas Sols-Morreale)Mirna Pérez‐Moreno(Universidad Autónoma de Madrid)Isabel Rodrigo(Instituto de Investigaciones Biomédicas Sols-Morreale)Annamaria Locascio(Instituto Cajal)Marı́a José Blanco(Instituto Cajal)Marta Garcia Del Barrio(Instituto Cajal)Francisco Portillo(Instituto de Investigaciones Biomédicas Sols-Morreale)M. Ángela Nieto(Instituto Cajal)

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Wnt/β-catenin signaling in development and cancer Cancer Cells and Metastasis Tissue Engineering and Regenerative MedicineSnailBiologyEpithelial–mesenchymal transitionCadherinMesenchymal stem cellTranscription factorCell biologyDownregulation and upregulationEmbryonic stem cellSNAI1

MeSH terms

Snail Family Transcription FactorsAnimalsBinding SitesCarcinomaCarcinoma, Squamous CellCell DifferentiationCell MovementCytoskeletal ProteinsDNA-Binding ProteinsEpithelial CellsHumansMesodermNeoplasm InvasivenessNeoplasms, Glandular and EpithelialPhenotype

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