articleTop 10% cited

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

European Journal of Pharmacology · 1990 · Vol. 185(1) · pp. 1–10

Ramón Trullás✉(National Institute of Diabetes and Digestive and Kidney Diseases)P. Skolnick(National Institute of Diabetes and Digestive and Kidney Diseases)

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Neuroscience and Neuropharmacology Research Memory and Neural Mechanisms Neurotransmitter Receptor Influence on BehaviorNMDA receptorNeuroscienceLong-term potentiationGlutamate receptorAgonistPharmacologyAntidepressantLong-term depressionPartial agonistPsychology

MeSH terms

Amino AcidsAmino Acids, CyclicAnimalsAntidepressive AgentsBehavior, AnimalBrain ChemistryDose-Response Relationship, DrugImipramineImmobilizationMaleMice, Inbred C57BLMotor ActivitySynaptic TransmissionStress, PsychologicalStrychnine

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776

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3.78

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95%

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The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression