reviewTop 1% cited
The validity of animal models of depression
Psychopharmacology · 1984 · Vol. 83(1) · pp. 1–16
Paul Willner✉(London Borough of Camden)
Neurotransmitter Receptor Influence on BehaviorStress Responses and CortisolNeuroendocrine regulation and behaviorFace validityPredictive validityLearned helplessnessPsychologyConstruct validityAnimal modelAnimal models of depressionDepression (economics)Developmental psychologyClinical psychology
MeSH terms
AmphetamineAnimalsBehavior, AnimalCircadian RhythmDepressive DisorderDisease Models, AnimalDihydroxyphenylalanineDrug SynergismHelplessness, LearnedHumans5-HydroxytryptophanKindling, NeurologicMotor ActivityOlfactory BulbPredatory Behavior
Citations
1,391
FWCI
8.25
field-weighted impact
References
218
Percentile
99%
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References
Bereavement: Studies of grief in adult life
Journal of Psychosomatic Research · 1976 · 1,237 citations
Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity
European Journal of Pharmacology · 1979 · 573 citations
Behavioural despair in rats: A new model sensitive to antidepressant treatments
European Journal of Pharmacology · 1978 · 3,115 citations
Acute and chronic stress effects on open field activity in the rat: Implications for a model of depression
Neuroscience & Biobehavioral Reviews · 1981 · 874 citations
A permanent change in brain function resulting from daily electrical stimulation
Experimental Neurology · 1969 · 3,057 citations
Mode of action of antidepressant drugs
Biochemical Pharmacology · 1978 · 517 citations
Specificity of the learned helplessness model of depression
Pharmacology Biochemistry and Behavior · 1982 · 384 citations
“Behavioural despair” in rats and mice: Strain differences and the effects of imipramine
European Journal of Pharmacology · 1978 · 627 citations
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The validity of animal models of depression
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