review Open AccessTop 10% cited
Drug–protein binding: a critical review of analytical tools
Analytical and Bioanalytical Chemistry · 2010 · Vol. 398(1) · pp. 53–66
Karine Vuignier✉(University of Geneva)Julie Schappler(University of Geneva)Jean‐Luc Veuthey(University of Lausanne)Pierre‐Alain Carrupt(University of Geneva)Sophie Martel(University of Lausanne)
Protein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsAntibiotics Pharmacokinetics and EfficacyDrugDrug discoveryBiochemical engineeringPlasma protein bindingComputer scienceComputational biologyPharmacodynamicsFree fractionPharmacokineticsChemistry
MeSH terms
AnimalsPharmaceutical PreparationsHumansProtein BindingProteinsDrug Discovery
Citations
385
FWCI
8.11
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References
129
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98%
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References
Binding constants: The measurement of molecular complex stability
European Journal of Medicinal Chemistry · 1987 · 1,787 citations
High throughput artificial membrane permeability assay for blood–brain barrier
European Journal of Medicinal Chemistry · 2003 · 1,123 citations
Physicochemical High Throughput Screening: Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes
Journal of Medicinal Chemistry · 1998 · 1,269 citations
Methods for the determination of binding constants by capillary electrophoresis
Electrophoresis · 2001 · 278 citations
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