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Physicochemical High Throughput Screening:  Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes

Journal of Medicinal Chemistry · 1998 · Vol. 41(7) · pp. 1007–1010
Manfred KansyFrank SennerKlaus Gubernator

Abstract

ADVERTISEMENT RETURN TO ISSUELetterNEXTPhysicochemical High Throughput Screening: Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption ProcessesManfred Kansy, Frank Senner, and Klaus GubernatorView Author Information F. Hoffmann-La Roche Ltd., Pharma Research, Infectious Diseases, Molecular Structure Research, 4070 Basel, Switzerland Cite this: J. Med. Chem. 1998, 41, 7, 1007–1010Publication Date (Web):March 7, 1998Publication History Received11 August 1997Published online7 March 1998Published inissue 1 March 1998https://pubs.acs.org/doi/10.1021/jm970530ehttps://doi.org/10.1021/jm970530erapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views11023Altmetric-Citations1029LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Absorption,Cells,Fluxes,Interface engineering,Membranes Get e-Alerts

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MeSH terms

AbsorptionAdsorptionDrug Evaluation, PreclinicalHumansHydrogen-Ion ConcentrationIntestinal AbsorptionMembranes, ArtificialPermeabilityPharmacokineticsSpectrophotometry, UltravioletCaco-2 Cells
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