articleTop 1% cited
Plasma transforming growth factor‐β1 level and efficacy of α‐tocopherol in patients with non‐alcoholic steatohepatitis: a pilot study
Alimentary Pharmacology & Therapeutics · 2001 · Vol. 15(10) · pp. 1667–1672
Tsukasa Hasegawa✉(Asahikawa Medical College Hospital)Masashi Yoneda(Dokkyo University)Kimihide Nakamura(Asahikawa Medical College Hospital)Isao Makino(Asahikawa Medical College Hospital)Akira Terano(Dokkyo University)
Abstract
Our data suggest that the measurement of the level of plasma transforming growth factor-beta1 represents a possible method of distinguishing between non-alcoholic steatohepatitis and non-alcoholic fatty liver. Long-term alpha-tocopherol treatment may be safe and effective for non-alcoholic steatohepatitis. A randomized, controlled, double-blind trial is needed to confirm the full potential of alpha-tocopherol in the management of non-alcoholic steatohepatitis.
Liver Disease Diagnosis and TreatmentLiver Disease and TransplantationLiver physiology and pathologySteatohepatitisMedicineAlcoholic hepatitisFatty liverInternal medicineGastroenterologyAlcoholic liver diseaseCirrhosisAlanine transaminaseFibrosis
MeSH terms
AdultAlanine TransaminaseAlkaline PhosphataseAspartate AminotransferasesBody WeightCholesterolFatty LiverFemalegamma-GlutamyltransferaseHepatitisHumansLiver CirrhosisMalePilot ProjectsTriglycerides
Funding
- Smoking Research Foundation
Citations
406
FWCI
14.63
field-weighted impact
References
33
Percentile
99%
vs. same field & year
Citations per year
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References
The Natural History of Nonalcoholic Steatohepatitis: A Follow–Up Study of Forty–Two Patients for Up to 21 Years
Hepatology · 1990 · 1,491 citations
Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis†
Hepatology · 1981 · 3,560 citations
Nonalcoholic Steatohepatitis
Mayo Clinic Proceedings · 1980 · 2,875 citations
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