review Open AccessTop 1% cited
Drugging the undruggable RAS: Mission Possible?
Nature Reviews Drug Discovery · 2014 · Vol. 13(11) · pp. 828–851
Adrienne D. Cox✉(University of North Carolina at Chapel Hill)Stephen W. Fesik(Vanderbilt University)Alec C. Kimmelman(Dana-Farber Cancer Institute)Ji Luo(National Cancer Institute)Channing J. Der(University of North Carolina at Chapel Hill)
Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerProtein Degradation and InhibitorsEffectorComputational biologyBiologyBioinformaticsComputer scienceCell biology
MeSH terms
AnimalsAntineoplastic AgentsHumansSignal TransductionOncogene Proteinsras Proteins
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