review Open AccessTop 1% cited
The apical conjugate efflux pump ABCC2 (MRP2)
Pflügers Archiv - European Journal of Physiology · 2006 · Vol. 453(5) · pp. 643–659
Anne T. Nies✉(German Cancer Research Center)Dietrich Keppler(Heidelberg University)
Drug Transport and Resistance MechanismsNeonatal Health and BiochemistryPediatric Hepatobiliary Diseases and TreatmentsMultidrug resistance-associated protein 2EffluxApical membraneChemistryXenobioticGlucuronateBiochemistryEpithelial polarityBiologyTransporter
MeSH terms
Multidrug Resistance-Associated Protein 2Amino Acid SequenceAnimalsBase SequenceBile CanaliculiCell MembraneDisease Models, AnimalGene Expression RegulationHumansJaundice, Chronic IdiopathicSubstrate SpecificityGenetic VariationMembrane Transport ProteinsATP-Binding Cassette, Sub-Family C ProteinsMultidrug Resistance-Associated Proteins
Funding
- Deutsches Krebsforschungszentrum
- Wilhelm Sander-Stiftung
- Deutsche Forschungsgemeinschaft
Citations
391
FWCI
12.11
field-weighted impact
References
199
Percentile
99%
vs. same field & year
Citations per year
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References
Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells
Molecular Pharmacology · 1999 · 680 citations
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 801 citations
The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of<i>CYP3A4</i>by Rifampicin through a Distal Enhancer Module
Molecular Pharmacology · 1999 · 642 citations
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The apical conjugate efflux pump ABCC2 (MRP2)
Pflügers Archiv - European Journal of Physiology · 2006 · 391 citations
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