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Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss

Cell stem cell · 2007 · Vol. 1(1) · pp. 113–126
Yaroslava RuzankinaCarolina Pinzon‐GuzmanAmma AsareTony OngLaura PontanoGeorge CotsarelisValerie P. ZediakMarielena VelezAvinash BhandoolaEric J. Brown
Nuclear Receptors and SignalingRetinoids in leukemia and cellular processesRNA regulation and diseaseBiologyPhenotypePremature agingStem cellProgenitor cellThymic involutionHair lossInvolution (esoterism)Knockout mouseCell biology

MeSH terms

AgingAnimalsPhenotypeStem CellsProtein Serine-Threonine KinasesMice, KnockoutCell Cycle ProteinsGenes, EssentialMiceAtaxia Telangiectasia Mutated Proteins

Funding

  • University of Connecticut
  • National Institute on Aging
Citations
800
FWCI
9.87
field-weighted impact
References
43
Percentile
99%
vs. same field & year
Citations per year
References
Regulation of Cre Recombinase Activity by Mutated Estrogen Receptor Ligand-Binding Domains
Biochemical and Biophysical Research Communications · 1997 · 995 citations
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Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss · Scinovex