article Open AccessTop 1% cited
TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
Cancer Cell · 2005 · Vol. 8(5) · pp. 369–380
Dori A. Thomas✉(Memorial Sloan Kettering Cancer Center)Joan Massagué(Memorial Sloan Kettering Cancer Center)
TGF-β signaling in diseasesPancreatic and Hepatic Oncology ResearchCancer Cells and MetastasisImmune surveillanceCytotoxic T cellEvasion (ethics)Immune systemCancer researchTransforming growth factorBiologyImmunologyCell biologyGenetics
MeSH terms
AnimalsBlood ProteinsCytotoxicity, ImmunologicInterferon-gammaInterleukin-2Serine EndopeptidasesT-Lymphocytes, CytotoxicGene Expression Regulation, NeoplasticTransforming Growth Factor betaTumor EscapeGene Expression ProfilingCell Line, TumorCell ProliferationMiceActivating Transcription Factors
Funding
- Howard Hughes Medical Institute
- Memorial Sloan-Kettering Cancer Center
Citations
1,307
FWCI
14.38
field-weighted impact
References
50
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99%
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References
TGF-β signaling in tumor suppression and cancer progression
Nature Genetics · 2001 · 2,272 citations
Smad transcription factors
Genes & Development · 2005 · 2,431 citations
The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis
Gene · 2001 · 819 citations
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
Cell · 2003 · 5,831 citations
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