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YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells

Current Biology · 2007 · Vol. 17(23) · pp. 2054–2060

Fernando D. Camargo✉(Whitehead Institute for Biomedical Research)Sumita Gokhale(Whitehead Institute for Biomedical Research)Jonathan B. Johnnidis(Whitehead Institute for Biomedical Research)Dongdong Fu(Whitehead Institute for Biomedical Research)George W. Bell(Whitehead Institute for Biomedical Research)Rudolf Jaenisch(Whitehead Institute for Biomedical Research)Thijn R. Brummelkamp✉(Whitehead Institute for Biomedical Research)

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Hippo pathway signaling and YAP/TAZ Cancer-related Molecular Pathways Epigenetics and DNA MethylationBiologyProgenitor cellProgenitorYAP1Cell biologyPhysiologyZoologyStem cellGeneticsTranscription factor

MeSH terms

YAP-Signaling ProteinsAdenomaAnimalsCell DifferentiationHumansIntestine, SmallLiverMice, TransgenicOrgan SizePhosphoproteinsStem CellsTranscription FactorsColorectal NeoplasmsSignal TransductionOligonucleotide Array Sequence Analysis