articleTop 1% cited

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

Nature Cell Biology · 2015 · Vol. 17(3) · pp. 288–299

Diego L. Medina✉(Telethon Institute Of Genetics And Medicine)Simone Di Paola(Telethon Institute Of Genetics And Medicine)Ivana Peluso(Telethon Institute Of Genetics And Medicine)Andrea Armani(University of Padua)Diego De Stefani(Neuroscience Institute)Rossella Venditti(Telethon Institute Of Genetics And Medicine)Sandro Montefusco(Telethon Institute Of Genetics And Medicine)Anna Scotto Rosato(Telethon Institute Of Genetics And Medicine)Carolina Prezioso(Telethon Institute Of Genetics And Medicine)Alison Forrester(Telethon Institute Of Genetics And Medicine)Carmine Settembre(Telethon Institute Of Genetics And Medicine)Wuyang Wang(University of Michigan–Ann Arbor)Qiong Gao(University of Michigan–Ann Arbor)Haoxing Xu(University of Michigan–Ann Arbor)Marco Sandri(University of Padua)Rosario Rizzuto(University of Padua)Maria Antonietta De Matteis(Telethon Institute Of Genetics And Medicine)Andrea Ballabio(Telethon Institute Of Genetics And Medicine)

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Calcium signaling and nucleotide metabolism Signaling Pathways in Disease Autophagy in Disease and TherapyTFEBAutophagyCell biologyLysosomeCalcineurinBiologyCalcium signalingmTORC1BiogenesisSignal transduction

MeSH terms

AnimalsAutophagyFibroblastsGene Expression RegulationHumansLysosomesPhosphorylationCalcineurinCalcium SignalingProtein TransportCell Line, TumorTransient Receptor Potential ChannelsMiceBasic Helix-Loop-Helix Leucine Zipper Transcription Factors

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Autophagy: The spotlight for cellular stress responses